Preventing radiation damage with melanin-based material - C&EN

Researchers have developed edible nanoparticles made from melanin that could protect the intestines from damage caused by radiotherapy for abdominal and pelvic cancers. The nanoparticles, synthesized from selenium-modified melanin, were shown to withstand stomach conditions and protect human cells from radiation-induced damage. In tests on mice, those injected with the nanoparticles survived longer and showed less intestinal damage compared to untreated mice. This advancement may provide a more effective oral solution for protecting the gut during cancer treatments, addressing limitations of current injectable radioprotection drugs. Experts view this preclinical study as a promising step towards potential human applications.

Fri, 19 Sep 2025 17:41:17 GMT | C&EN