A new PET tracer, 64Cu-NOTA-EV-F(ab′)2, has been developed that can visualize the protein nectin-4, commonly overexpressed in triple-negative breast cancer (TNBC) and urothelial bladder cancer (UBC), within just four hours. This same-day imaging technique can assist in patient treatment decisions, minimizing ineffective therapy exposure. Researchers evaluated the tracer's effectiveness, with findings showing significant tumor accumulation and specificity for nectin-4, making it a promising tool for noninvasive cancer monitoring. The study's lead researchers suggest this method could extend to various cancers, enhancing molecular imaging efficacy and patient safety.
Thu, 18 Sep 2025 20:54:53 GMT | Imaging Technology News